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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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Of Viroids and Prions.

Theodor O Diener1

  • 1Department of Molecular Genetics, University of Maryland, College Park, MD 20472, USA. tod26@juno.com.

Viruses
|November 28, 2018
PubMed
Summary

This 2017 monograph provides a comprehensive overview of viroids and satellites, detailing known species and their molecular biology. It serves as a vital resource for plant pathologists seeking in-depth knowledge on these plant pathogens.

Area of Science:

  • Plant Pathology
  • Molecular Biology
  • Virology

Background:

  • The 2017 monograph "Viroids and Satellites" offers a detailed compendium of known viroid and viroid-like satellite species.
  • Authored by over 100 experts from 24 countries, the book covers diverse perspectives on these plant pathogens.

Discussion:

  • The monograph addresses the need for a consolidated resource on viroids and satellites, subjects often unfamiliar to many.
  • It emphasizes the importance of including basic molecular biology information for practical plant pathologists.

Key Insights:

  • The book details numerous viroid and satellite species from multiple viewpoints.
  • A dedicated chapter on molecular biology is included to aid practical application.

Outlook:

Keywords:
HIVRNAprionssubviral pathogensviroids

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  • This comprehensive resource aims to enhance understanding and practical application of knowledge on viroids and satellites.
  • It serves as a foundational text for researchers and practitioners in plant pathology.