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Updated: Feb 2, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
An observational study on the clinical features of esophageal cancer followed by multiple primary cancers
Zhipeng Hu1, Min Zhang1, Zhiwei Wang1
1Department of Cardiovascular Surgery, Renmin hospital of Wuhan University, 238 Jiefang Road, Wuhan City of Hubei Provice, PR China.
Aim:
To investigate the nature of multiple primary cancers initiated by esophageal cancer-multiple primary cancers (EC-MPC).
Patients & Methods:
SEER data about patients'/tumor characteristics, and survival were analyzed and compared.
Results & Conclusion:
1727 of 29,733 registered EC patients have EC-MPC. Individuals diagnosed at 60-79 years old, earlier stage and/or moderately differentiated EC were more likely to get EC-MPC. Fewer patients in the EC-MPC group suffered from metastases. Patients in the EC-MPC group showed a longer survival rate and lower EC-specific deaths. Other factors like age, sex, race, tumor differentiation and Tumor, Node, Metastasis stage also affected survival. Radiation can improve survival. EC-MPC patients have some distinct features compared with solitary EC.
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