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Related Experiment Video

Updated: Feb 2, 2026

Author Spotlight: Exploring ShiDuGao's Multi-Target Approach in Anus Eczema Treatment
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Eczema and subsequent suicide: a matched case-control study.

Aaron Mark Drucker1,2,3, Deva Thiruchelvam4, Donald A Redelmeier4,5,6,7

  • 1Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

BMJ Open
|November 28, 2018
PubMed
Summary
This summary is machine-generated.

Individuals with persistent eczema face a slightly higher risk of suicide death. This association is linked to mental health factors, and the overall risk remains low, highlighting opportunities for physician intervention.

Keywords:
dermatological epidemiologyeczemaepidemiology

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Area of Science:

  • Epidemiology
  • Psychiatry
  • Dermatology

Background:

  • Eczema is a chronic inflammatory skin condition affecting millions globally.
  • Mental health comorbidities are frequently observed in patients with chronic diseases.
  • Suicide remains a significant public health concern, necessitating research into associated risk factors.

Purpose of the Study:

  • To investigate the association between persistent eczema and the risk of suicide death.
  • To determine if this association is mediated by other known suicide risk factors.
  • To inform clinical practice regarding suicide prevention in eczema patients.

Main Methods:

  • A double-matched case-control study was conducted using data from Ontario, Canada.
  • 18,441 suicide cases were matched with 36,882 controls (1:2 ratio) based on age, sex, and socioeconomic status.
  • Persistent eczema was defined as five or more physician visits for the diagnosis within five years.

Main Results:

  • A history of persistent eczema was associated with a 22% increased risk of suicide death (OR 1.22, 95% CI 1.01 to 1.48).
  • The association between eczema and suicide risk was largely explained by major suicide risk factors.
  • A significant proportion of suicide cases with eczema had recent physician contact, with some seeking care for eczema.

Conclusions:

  • Patients with persistent eczema have a modestly increased risk of suicide death, though the absolute risk is low.
  • The observed association is influenced by underlying mental health conditions.
  • Healthcare providers have a crucial role in identifying and intervening for suicide prevention in patients with eczema.