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Updated: Feb 2, 2026

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Published on: August 16, 2020
Safwan S Halabi1, Luciano M Prevedello1, Jayashree Kalpathy-Cramer1
1From the Department of Radiology, Stanford University, 300 Pasteur Dr, MC 5105, Stanford, CA 94305 (S.S.H.); Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, Ohio (L.M.P.); Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, Mass (J.K.C.); Massachusetts General Hospital & Brigham and Women's Hospital Center for Clinical Data Science, Boston, Mass (A.B.M., K.A.); Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.B.); Department of Radiology, St. Michael's Hospital, Toronto, Ontario, Canada (M.C.); Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI (I.P.); Universidade Federal de Goiás, Goiânia, Brazil (L.A.P., R.T.S.); Universidade Federal de São Paulo, São Paulo, Brazil (N.A., F.C.K.); Visiana, Hørsholm, Denmark (H.H.T.); MD.ai, New York, NY (L.C.); Department of Radiology, Weill Cornell Medicine, New York, NY (G.S.) Department of Radiology, University of California-San Francisco, San Francisco, Calif (M.D.K.); Department of Radiology, Mayo Clinic, Rochester, Minn (B.J.E.); and Department of Radiology, Thomas Jefferson University, Philadelphia, Pa (A.E.F.).
The Radiological Society of North America (RSNA) Pediatric Bone Age Machine Learning Challenge successfully applied artificial intelligence (AI) and machine learning (ML) to determine bone age in pediatric hand radiographs, achieving high accuracy. This initiative fostered collaboration and advanced AI development for improved diagnostic accuracy in medical imaging.
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