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Neisseria mucosa Peritonitis in the Setting of a Migrated Intrauterine Device
Kiran Nawaz Khan1, Ramesh Saxena1, Michael Choti2
1Division of Nephrology, University of Texas Southwestern, Dallas, Texas, U.S.A.
Abstract:
Peritonitis is a major complication in peritoneal dialysis (PD) patients, often requiring a switch to hemodialysis (HD). Common sources of bacterial peritonitis are touch contamination and PD catheter-related infection. Intra-abdominal pathology is a less common cause of peritonitis in PD patients, and rarely is Neisseria mucosa the causative organism.We present an uncommon case of N. mucosa peritonitis in a 30-year-old African American female patient treated with nocturnal intermittent PD. The infection occurred in the setting of a translocated intrauterine contraceptive device (IUCD) in the infrahepatic region because of transmural migration. Our patient underwent laparoscopic removal of the IUCD and received empiric intraperitoneal (IP) vancomycin and intravenous ceftriaxone. After the isolate was identified as N. mucosa, her regimen was changed to IP ceftriaxone for a total of 21 days. Cell count after completion of antibiotics showed resolution of the peritonitis. The PD catheter was salvaged and transition to HD was avoided.
Insights
Peritonitis in peritoneal dialysis (PD) patients can be serious. This case highlights Neisseria mucosa peritonitis caused by a translocated intrauterine contraceptive device (IUCD), successfully treated without PD catheter removal.
Area of Science:
- Nephrology
- Infectious Diseases
- Gastroenterology
Background:
- Peritonitis is a significant complication for patients undergoing peritoneal dialysis (PD), frequently necessitating a transition to hemodialysis (HD).
- Common causes include touch contamination and PD catheter-related infections, while intra-abdominal pathology is less frequent.
- Neisseria mucosa is an uncommon pathogen implicated in PD-related peritonitis.
Observation:
- A 30-year-old female on nocturnal intermittent PD presented with peritonitis.
- The infection was linked to a translocated intrauterine contraceptive device (IUCD) that migrated through the abdominal wall.
- The patient had an unusual case of Neisseria mucosa peritonitis.
Findings:
- The patient underwent laparoscopic removal of the translocated IUCD.
- Initial treatment involved empiric intraperitoneal (IP) vancomycin and intravenous ceftriaxone.
- Post-identification of N. mucosa, treatment was adjusted to IP ceftriaxone for 21 days, leading to peritonitis resolution.
Implications:
- This case demonstrates successful management of N. mucosa peritonitis in a PD patient with a translocated IUCD.
- Conservative management, including IUCD removal and targeted antibiotics, salvaged the PD catheter and avoided transition to HD.
- Highlights the importance of considering intra-abdominal pathology and unusual organisms in refractory or recurrent PD peritonitis.
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