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Related Experiment Videos

Pseudophakic bullous keratopathy.

E J Cohen1, S E Brady, K Leavitt

  • 1Cornea Service, Wills Eye Hospital, Philadelphia, Pennsylvania 19107.

American Journal of Ophthalmology
|September 15, 1988
PubMed
Summary
This summary is machine-generated.

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Pseudophakic bullous keratopathy, often linked to anterior chamber intraocular lenses, causes significant vision loss. While penetrating keratoplasty can improve vision, some visual impairment may persist even with clear grafts.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Intraocular Lens Implantation

Background:

  • Pseudophakic bullous keratopathy (PBK) is a serious complication following cataract surgery.
  • Anterior chamber intraocular lenses (ACIOLs), particularly certain styles, have been implicated in PBK development.

Purpose of the Study:

  • To identify predisposing factors for PBK.
  • To analyze associated complications, management strategies, and visual outcomes in PBK patients.
  • To evaluate the effectiveness of penetrating keratoplasty for PBK.

Main Methods:

  • Retrospective review of 271 eyes from 251 patients diagnosed with PBK over a six-month period.
  • Analysis of patient records to determine lens type, visual acuity, previous interventions, and follow-up data.

Related Experiment Videos

  • Assessment of graft clarity and visual outcomes post-keratoplasty.

    • Main Results:

    • ACIOLs, especially Leiske-style lenses, were frequently associated with PBK (155/271 eyes).
    • Initial visual acuity was poor in many cases (206/271 eyes ≤ 20/200).
    • Penetrating keratoplasty was performed in 189 eyes; 108/189 had ≤ 20/200 vision post-operatively, but vision improved with longer follow-up (23/36 eyes ≥ 20/100 with ≥ 2 years follow-up).
    • Despite clear grafts in most cases (145/189), 29/92 eyes had permanent visual loss after one year.

    Conclusions:

    • PBK is strongly associated with specific types of ACIOLs, leading to significant visual impairment.
    • Penetrating keratoplasty can restore vision in many PBK patients, with outcomes improving over time.
    • A subset of patients may experience persistent visual loss despite successful graft survival, highlighting the complexity of PBK management.