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Related Experiment Video

Updated: Feb 2, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

Content validation of a questionnaire measuring basic perinatal depression knowledge.

Sarira El-Den¹, Claire L O'Reilly¹, David M Gardner²

¹a School of Pharmacy , The University of Sydney , Camperdown , New South Wales , Australia.

|November 28, 2018

Summary

A new questionnaire was developed and validated to assess basic knowledge of perinatal depression (PND) among pharmacists and healthcare professionals. This tool aims to improve PND screening and care in primary healthcare settings.

Keywords:

Content validity knowledge perinatal depression questionnaire

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Area of Science:

Healthcare Professional Education
Mental Health Assessment
Perinatal Health Research

Background:

Perinatal depression (PND) screening is recommended in healthcare settings.
There is a need for validated tools to assess PND knowledge among primary healthcare professionals (HCPs).

Purpose of the Study:

To develop and content validate a basic PND knowledge questionnaire for pharmacists and other HCPs.
To ensure the questionnaire accurately measures essential PND knowledge.

Main Methods:

A six-item questionnaire was created.
Content validation was performed by 25 perinatal mental health experts.
The Content Validity Index (CVI) was used to assess validity, with a CVI > 0.8 indicating validity.

Main Results:

Ten experts participated in the validation process.
Five out of six items achieved a CVI score of 0.9 or 1.0.
The overall questionnaire CVI was 0.83, indicating good content validity.
Expert feedback led to minor revisions in questions and response options.

Conclusions:

The developed questionnaire is content-validated for assessing basic PND knowledge in pharmacists and HCPs.
Expert comments highlighted the need for consistent definitions of PND onset and prevalence in research.
This tool can support PND education and screening initiatives within primary care.