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Updated: Feb 2, 2026

Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Persistent local demucosalization after endoscopic sinus surgery: A report of 3 cases
Conner J Massey1, Menka M Sanghvi, Thomas R Troost
1Department of Otolaryngology, University of Colorado School of Medicine, 12631 E. 17th Ave., B-205, Aurora, CO 80045, USA. conner.massey@ucdenver.edu.
Persistent demucosalization after endoscopic sinus surgery (ESS) can occur. Surgical debridement, alongside intensive wound care, effectively treated this rare complication in three patients, promoting mucosal healing.
Area of Science:
- Otolaryngology
- Surgical Pathology
Background:
- Mucosal preservation is crucial for successful endoscopic sinus surgery (ESS) outcomes.
- Persistent demucosalization, a rare complication of ESS, can be resistant to conservative treatments.
Purpose of the Study:
- To evaluate the effectiveness of surgical debridement for managing persistent demucosalization after ESS.
- To identify potential underlying causes and effective treatment strategies for this rare complication.
Main Methods:
- Retrospective review of three patients with persistent demucosalization post-ESS.
- Analysis of wound management strategies including mechanical debridement, gelatin sponge placement, and intensive moisturization.
- Consideration of biopsy and culture for identifying underlying disease processes or infections.
Main Results:
- Two of three patients achieved successful remucosalization with the described treatment approach.
- The intervention involved mechanical debridement, gelatin sponge placement, and intensive moisturization therapy.
Conclusions:
- Surgical debridement may be an effective strategy for chronic, persistent demucosalized wounds following ESS.
- Biopsy and culture can aid in diagnosing and managing rare, persistent postoperative complications of ESS.
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