Related Experiment Video

Updated: Feb 2, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

22.3K

Falls in frontotemporal dementia and related syndromes

James R Burrell1, John R Hodges2

  • 1Concord Clinical School, Sydney Medical School, University of Sydney, Sydney, Australia; Brain and Mind Centre, University of Sydney Medical School, Sydney, NSW, Australia.

Handbook of Clinical Neurology
|November 29, 2018
PubMed

Insights

Falls are common in frontotemporal dementia (FTD) and related disorders, particularly those with motor symptoms. More research is needed to understand fall risks and develop management strategies for this younger-onset dementia.

Area of Science:

  • Neurology
  • Gerontology

Background:

  • Frontotemporal dementia (FTD) is a significant cause of early-onset dementia.
  • Falls are a serious concern in FTD but are underreported and understudied.
  • FTD often co-occurs with motor neuron disease (MND) and atypical parkinsonian syndromes like progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS).

Purpose of the Study:

  • To review the clinical features of FTD and related syndromes.
  • To highlight the frequent occurrence of falls in FTD patients.
  • To emphasize the need for further research on falls in FTD.

Main Methods:

  • Literature review of clinical features of FTD and related disorders.
  • Analysis of the association between cognitive and motor symptoms and falls.
  • Identification of knowledge gaps regarding falls in FTD.

Main Results:

  • Falls are frequently observed in patients with FTD syndromes.
  • Motor symptoms and signs, especially in FTD overlapping with PSP, CBS, or MND, present the highest fall risk.
  • Cognitive impairment also contributes to falls, but motor deficits appear more critical.

Conclusions:

  • Falls are a prevalent issue in frontotemporal dementia and related conditions.
  • Motor impairments significantly increase fall risk in FTD.
  • Systematic studies are crucial to determine fall frequency, timing, and complications to inform treatment strategies.
Keywords:
corticobasal syndromefallsfrontotemporal dementiamotor neuron diseaseprogressive supranuclear palsy

More Related Videos

Design and Analysis for Fall Detection System Simplification08:05

Design and Analysis for Fall Detection System Simplification

Published on: April 6, 2020

11.2K
Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome08:31

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

Published on: July 31, 2016

14.5K

Related Concept Videos

Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
577
Free-falling Bodies: Example01:05

Free-falling Bodies: Example

An object falling without any air resistance under the influence of gravitational force is said to be in free-fall. For free-falling bodies, the acceleration due to gravity is constant, irrespective of their mass. Free-fall is experienced not only by objects falling downward, but also by all objects whose motion is influenced by gravitational force alone. The dynamics of free-fall motion can be calculated using kinematic equations of motion, since free-fall acceleration is constant.
The...
31.7K
Free-falling Bodies: Introduction01:07

Free-falling Bodies: Introduction

All objects, neglecting air resistance, fall with the same acceleration towards the Earth's center due to the force exerted by the Earth's gravity. This experimentally determined fact is unexpected because we are so accustomed to the effects of air resistance and friction that we expect light objects to fall slower than heavier ones. People believed that a heavier object had a greater acceleration when falling until Galileo Galilei (1564–1642) proved otherwise. We now know this is...
11.9K
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
641
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.0K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
1.0K