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A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
Published on: June 20, 2017
Mild traumatic brain injury and concussion: terminology and classification
Eric S Sussman1, Arjun V Pendharkar1, Allen L Ho1
1Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA, United States.
Abstract:
Traumatic brain injury (TBI) is a major cause of morbidity and mortality throughout the world. Mild TBI, which is typically defined by Glasgow Coma Scale score ≥13, accounts for the vast majority of all TBIs, particularly in the setting of sports-related injuries. The terms concussion and TBI are often used interchangeably, both in the medical literature and in clinical care of this patient population. However, the lack of clearly defined definitions of these terms often leads to confusion, and this confusion may lead to delayed diagnosis and inconsistent management of affected patients. Here, we review the current terminology and classification of mild TBI and concussion. We will also discuss recent efforts to stratify these injuries into clinically relevant subtypes or profiles that are both diagnostic- and treatment-targeted.
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