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Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein
G G Glenner1, E D Eanes, C A Wiley
1University of California, San Diego, La Jolla 92093.
Biochemical and Biophysical Research Communications
|September 15, 1988
Abstract:
A synthetic peptide formed from residues 20-29 of the pancreatic islet amyloid protein has the confirmation of a twisted beta-pleated sheet protein suggesting it is a potential contributor toward amyloid fibril formation in the islets of Langerhans in Type 2 diabetes mellitus.