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Related Experiment Video

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Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration
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Gait in children with infantile/atypical autism: Age-dependent decrease in gait variability and associations with

Olivia Manicolo1, Mark Brotzmann2, Priska Hagmann-von Arx1

  • 1Department of Psychology, University of Basel, Missionsstrasse 62, 4055 Basel, Switzerland.

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
|November 29, 2018
PubMed
Summary

Children with autism spectrum disorder exhibit greater gait variability, impacting their walking patterns. This variability lessens with age and correlates with motor skills, suggesting developmental improvements in gait regularity.

Keywords:
ASDChildrenGait maturationGait variabilityMotor milestonesMotor skills

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Area of Science:

  • Developmental Pediatrics
  • Neuroscience
  • Biomechanical Engineering

Background:

  • Autism spectrum disorder (ASD) is a neurodevelopmental condition often associated with motor challenges.
  • Gait abnormalities and variability in motor skills are frequently observed in children with ASD.
  • Understanding the relationship between gait, motor development, and age is crucial for early intervention.

Purpose of the Study:

  • To investigate gait characteristics in children with infantile/atypical autism compared to typically developing controls.
  • To examine the associations between gait parameters, prewalking motor milestones, and motor skills in children with ASD.
  • To explore the influence of age on gait variability in children with ASD.

Main Methods:

  • GAITRite system used to record spatiotemporal and variability gait parameters in 32 children with ASD and 36 controls.
  • Parental reports on prewalking motor milestones.
  • Movement Assessment Battery for Children (MABC) used to assess motor skills.

Main Results:

  • Children with ASD demonstrated significantly higher gait variability, indicating less regular walking patterns.
  • Gait variability in children with ASD was negatively associated with motor skills but not prewalking milestones.
  • Gait variability in children with ASD decreased with age, showing convergence towards typical development.

Conclusions:

  • Increased gait variability is a characteristic feature in children with infantile/atypical autism.
  • Motor skill development, rather than early motor milestones, is linked to gait regularity in this population.
  • Gait regularity in children with ASD improves with age, suggesting a potential for developmental catch-up.