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Updated: Feb 2, 2026

Terminal H-reflex Measurements in Mice
Published on: June 16, 2022
Capecitabine-Associated Terminal Ileitis
Irene E G van Hellemond1, Annemarie M Thijs1, Geert-Jan Creemers1
1Department of Internal Medicine, Catharina Hospital, Eindhoven, the Netherlands.
Abstract:
Capecitabine is an oral fluoropyrimidine used as adjuvant and palliative chemotherapy in patients with colorectal cancer. Diarrhea is a well-known side effect of capecitabine and 5-fluorouracil agents. We present a case with terminal ileitis as a rare adverse event of capecitabine treatment. Capecitabine-induced terminal ileitis is likely to be underreported. It should be considered more often as a cause of severe and atypical complaints of diarrhea during treatment with capecitabine or other 5-fluorouracil agents.
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