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Whole Body Vibration Methods with Survivors of Polio
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Enterovirus D68 - The New Polio?

Hayley Cassidy1, Randy Poelman1, Marjolein Knoester1

  • 1Department of Medical Microbiology and Infection Prevention, Division of Clinical Virology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.

Frontiers in Microbiology
|November 29, 2018
PubMed
Summary
This summary is machine-generated.

Enterovirus D68 (EV-D68) is a growing global health concern, potentially causing Acute Flaccid Myelitis (AFM). Enhanced surveillance and diagnostics are crucial to manage this emerging infectious disease threat.

Keywords:
Enterovirus D68emergingoutbreak responsepathogenicitysurveillance

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Area of Science:

  • Virology and Epidemiology
  • Infectious Diseases
  • Neurology

Background:

  • Enterovirus D68 (EV-D68) has re-emerged globally, with increased outbreaks noted in recent years.
  • Enhanced clinical awareness and surveillance of non-polio enteroviruses have accompanied the rise in EV-D68 cases.
  • EV-D68's neurotropic properties and altered pathogenicity link it as a probable cause of Acute Flaccid Myelitis (AFM).

Purpose of the Study:

  • To highlight the emerging threat of Enterovirus D68 (EV-D68) as a cause of Acute Flaccid Myelitis (AFM).
  • To discuss the potential of EV-D68 to become a significant public health issue, drawing parallels with historical poliovirus outbreaks.
  • To emphasize the need for improved clinical recognition, diagnostics, and surveillance for EV-D68.

Main Methods:

  • Review of recent global outbreaks and clinical observations of Enterovirus D68.
  • Analysis of scientific literature on EV-D68's neurotropism and pathogenicity.
  • Comparison of the EV-D68 emergence with historical poliovirus epidemiology.

Main Results:

  • EV-D68 is increasingly recognized as a cause of Acute Flaccid Myelitis (AFM) globally.
  • The pattern of EV-D68 outbreaks and its neurological impact resemble historical poliovirus epidemics.
  • Current diagnostic and surveillance systems may underestimate the true burden of EV-D68 disease.

Conclusions:

  • Enterovirus D68 (EV-D68) represents a significant and growing public health challenge.
  • Effective prevention of EV-D68 as a widespread threat requires enhanced clinician awareness, robust diagnostics, and integrated surveillance systems.
  • Promoting data sharing within surveillance networks is essential to fully understand and mitigate the impact of EV-D68.