Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optical spectroscopy. Pre-mammography marker.

R L Egan1, P D Dolan

  • 1Department of Radiology, Emory University, Atlanta 30322.

Acta Radiologica (Stockholm, Sweden : 1987)
|September 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thiouracil in the treatment of hyperthyroidism.

The Nebraska state medical journal·2010
Same author

Thiouracil in the management of hyperthyroidism.

The Journal-lancet·2010
Same author

Graduate medical education in the United States.

JAMA·1989
Same author

Recent events of special interest to medical education.

JAMA·1986
Same author

Recent events of special interest to medical education.

JAMA·1985
Same author

Recent events of special interest to medical education.

JAMA·1984
Same journal

Radiomics based on MRI for preoperative prediction of the tumor budding grade in rectal cancer: a systematic review and meta-analysis.

Acta radiologica (Stockholm, Sweden : 1987)·2026
Same journal

Improved pancreatic imaging with photon-counting CT: a retrospective comparison with conventional CT.

Acta radiologica (Stockholm, Sweden : 1987)·2026
Same journal

The role of ultrasonography in diagnosing cystic adventitial disease.

Acta radiologica (Stockholm, Sweden : 1987)·2026
Same journal

Exploring artificial intelligence in point-of-care and standard breast ultrasound: a paired reader study.

Acta radiologica (Stockholm, Sweden : 1987)·2026
Same journal

Diagnostic performance of contrast-enhanced ultrasound for thyroid nodule characterization: a systematic review and meta-analysis.

Acta radiologica (Stockholm, Sweden : 1987)·2026
Same journal

Dynamic breast magnetic resonance imaging features and pathological correlation of patients diagnosed with breast cancer under the age of 40.

Acta radiologica (Stockholm, Sweden : 1987)·2026
See all related articles

Non-invasive optical spectroscopy can identify women at higher risk for breast cancer. This inexpensive, quick test offers high accuracy, potentially improving mammography efficiency and early detection.

Area of Science:

  • Biomedical Optics
  • Medical Imaging
  • Cancer Diagnostics

Background:

  • Non-invasive optical spectroscopy analyzes breast tissue composition and physiology.
  • This technique serves as a pre-mammography tool for cancer risk assessment.
  • It relies on tissue biochemistry, differing from macroscopic imaging methods.

Purpose of the Study:

  • To evaluate the efficacy of non-invasive optical spectroscopy as a breast cancer risk marker.
  • To assess the diagnostic performance of optical spectroscopy compared to mammography and biopsy.
  • To determine if optical spectroscopy can improve mammography efficiency.

Main Methods:

  • Optical spectroscopy was performed on 1739 women referred for mammography.
  • Data analysis utilized an automated computerized approach.

Related Experiment Videos

  • Results were compared with histological data from 166 breast biopsies.

    • Main Results:

    • The spectroscopic analysis achieved 87% sensitivity, 74% specificity, and 99% negative predictive value.
    • A positive spectroscopic result indicated a 16.5-fold increased relative risk of breast cancer.
    • Identifying 87% of cancer cases in 28.7% of women could quadruple mammography efficiency.

    Conclusions:

    • Optical spectroscopy shows significant promise for identifying women at higher risk of breast cancer.
    • The method may detect cancers missed by mammography, such as non-infiltration carcinomas and calcifications.
    • This non-invasive approach could enhance breast cancer screening by optimizing mammography utilization.