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Ovarian size in postmenopausal women
R K Goswamy1, S Campbell, J P Royston
1Department of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry, Denmark Hill, London.
British Journal of Obstetrics and Gynaecology
|August 1, 1988
Summary
This study established reference ranges for ovarian volumes in postmenopausal women using pelvic ultrasonography. These findings aid in developing screening programs for ovarian cancer by identifying abnormal ovarian size.
Area of Science:
- Gynecology
- Radiology
- Oncology
Background:
- Ovarian cancer screening requires reliable methods to assess ovarian size in postmenopausal women.
- Pelvic ultrasonography is a key imaging modality for evaluating ovarian morphology.
Purpose of the Study:
- To determine reference ranges for ovarian volumes in healthy postmenopausal women.
- To identify factors influencing ovarian size in this demographic.
- To develop criteria for abnormal ovarian morphology for ovarian cancer screening.
Main Methods:
- Pelvic ultrasonography was performed on 2246 postmenopausal women.
- Statistical analysis identified predictors of ovarian volume.
- Reference ranges and scoring systems for abnormal ovarian volumes were calculated.
Main Results:
- Mean ovarian volumes were 3.58 ml (right) and 3.57 ml (left).
- Significant predictors included years since menopause, weight, parity, age at menopause, hormone replacement therapy, and breast cancer history.
- A scoring system and nomogram were developed to assess ovarian abnormality.
Conclusions:
- Established reference ranges and methods for assessing ovarian volume abnormality in postmenopausal women.
- Findings support the use of ultrasonography-derived ovarian volume measurements in ovarian cancer screening protocols.
- Ovarian volume is influenced by multiple demographic and clinical factors.