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Updated: Feb 2, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Cognitive screening test in primary care: cut points for low education
Juliana Emy Yokomizo1, Katrin Seeher2, Glaucia Martins de Oliveira3
1Universidade de São Paulo. Faculdade de Medicina. Programa Terceira Idade (PROTER), Instituto de Psiquiatria. São Paulo, SP, Brasil.
The Brazilian General Practitioner Assessment of Cognition (GPCOG-Br) accurately identifies cognitive impairment in primary care patients with low education, performing similarly to the Mini-Mental State Examination (MMSE). This tool is well-suited for clinical use.
Area of Science:
- Gerontology
- Cognitive Neurology
- Primary Care Medicine
Background:
- Cognitive impairment is a significant concern in aging populations.
- Accurate screening tools are crucial for early detection and intervention in primary care settings.
- The General Practitioner Assessment of Cognition (GPCOG) is a widely used cognitive screening tool, with its Brazilian version (GPCOG-Br) requiring validation.
Purpose of the Study:
- To evaluate the diagnostic accuracy of the Brazilian version of the General Practitioner Assessment of Cognition (GPCOG-Br).
- To compare the GPCOG-Br's performance against the Mini-Mental State Examination (MMSE).
- To assess these tools in individuals with low educational levels within Brazilian primary care.
Main Methods:
- A study involving 93 patients aged 60 and above from Brazilian primary care units.
- Data collected included sociodemographic, cognitive, and functional information.
- Statistical analyses employed receiver operating characteristic curves (AUC) and logistic regressions.
Main Results:
- The GPCOG-Br showed diagnostic accuracy comparable to the MMSE (AUC 0.90 vs. 0.91).
- Both tools demonstrated similar positive and negative predictive values.
- Adjusted cut-points yielded high sensitivity (86%) and satisfactory specificity (65%-80%), with lower education predicting poorer cognitive performance.
Conclusions:
- The GPCOG-Br is a clinically effective tool for cognitive assessment in Brazilian primary care.
- Its performance is comparable to the established MMSE, particularly in populations with limited education.
- The findings support the GPCOG-Br's utility for routine screening of cognitive function in primary care settings.
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