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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Appendicitis-II: Diagnostic Studies and Management01:29

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Laparoscopic versus open surgery for suspected appendicitis.

Thomas Jaschinski1, Christoph G Mosch, Michaela Eikermann

  • 1Institute for Research in Operative Medicine (IFOM) - Department for Evidence-based Health Services Research, University Witten/Herdecke, Ostmerheimer Str. 200 (Building 38), Cologne, Germany, 51109.

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|November 29, 2018
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Summary
This summary is machine-generated.

Laparoscopic appendectomy (LA) offers benefits over open appendectomy (OA) for adults, including less pain and faster recovery. However, LA in adults shows a higher risk of intra-abdominal abscesses. For children, LA reduces wound infections and hospital stays.

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Area of Science:

  • Surgical Procedures
  • Minimally Invasive Surgery
  • Gastrointestinal Surgery

Background:

  • Appendectomy is a common surgical procedure for acute appendicitis.
  • Open appendectomy (OA) has been the standard treatment.
  • Laparoscopic appendectomy (LA) offers a minimally invasive alternative.

Purpose of the Study:

  • To compare the benefits and harms of laparoscopic appendectomy (LA) versus open appendectomy (OA).

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials (RCTs) comparing LA and OA.
  • Searched multiple databases up to February 2018.
  • Included 85 RCTs with 9765 participants (adults and children).

Main Results:

  • In adults, LA reduced pain, wound infections, hospital stay, and time to normal activity, but increased intra-abdominal abscesses.
  • In children, LA reduced wound infections and hospital stay.
  • Evidence quality ranged from low to moderate, with some clinical effects being small.

Conclusions:

  • LA offers advantages over OA in adults for several outcomes, despite a higher risk of intra-abdominal abscesses.
  • LA shows benefits in wound infections and hospital stay for children.
  • Further high-quality research is needed, especially on quality of life in children.