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Updated: Feb 2, 2026

An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
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A statistical framework for radiation dose estimation with uncertainty quantification from the γ-H2AX assay

Jochen Einbeck1, Elizabeth A Ainsbury2, Rachel Sales1

  • 1Department of Mathematical Sciences, Durham University, Durham, United Kingdom.

Plos One
|November 29, 2018
PubMed
Summary

The gamma-H2AX focus assay is a reliable biomarker for ionizing radiation exposure. This study provides statistical models and a web applet for accurate dose estimation, addressing practical use limitations.

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