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Published on: June 20, 2020
The relationship between dietary inflammatory index (DII) and muscle mass and strength in Chinese children aged 6-9
William Kwame Amakye1, Zheqing Zhang1, Yuanhuan Wei1
1Department of Nutrition and Food Hygiene, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Insights
A higher dietary inflammatory index (DII) was linked to lower skeletal muscle mass in Chinese boys aged 6-9. No association was found in girls or with muscle strength in either sex.
Area of Science:
- Pediatric Nutrition
- Sports Medicine
- Human Physiology
Background:
- The Dietary Inflammatory Index (DII®) assesses diet's inflammatory potential.
- No prior studies have investigated the DII's impact on pediatric muscle mass or strength.
Purpose of the Study:
- To examine the association between the DII and skeletal muscle mass and strength in Chinese children aged 6-9 years.
Main Methods:
- 466 children (6-9 years) participated.
- Skeletal muscle mass (TSM, ASM, ALM) measured via DXA; indices calculated.
- Hand grip strength assessed; DII scores derived from a food frequency questionnaire.
Main Results:
- A significant inverse relationship was found between DII and various skeletal muscle mass measures in children.
- Children in the highest DII quartile had 1.04%–4.36% lower muscle mass compared to the lowest quartile.
- Inverse associations were significant in boys but not girls; no DII association with hand grip strength.
Conclusions:
- The DII is inversely associated with skeletal muscle mass in Chinese boys aged 6-9.
- No significant associations were observed between DII and skeletal muscle mass in girls or hand grip strength in either sex.
Background And Objectives:
The dietary inflammatory index (DII®) is a measure of the overall inflammatory potential of a person's diet. However, there have been no studies looking at the effect of DII on measures of muscle mass and strength. We aimed to examine the association between DII and skeletal muscle mass and strength in Chinese children.
Methods And Study Design:
A total of 466 children aged 6-9 years completed the study. Total body skeletal muscle mass (TSM), appendicular skeletal mass (ASM) and appendicular lean mass (ALM) were determined using Dual-energy X-ray absorptiometry. TSM/Height², TSM/Weight, ASM/Height² and ASM/Weight were calculated. The residual method was applied to compute ALM index (ALMI) adjusted for height and body fat. Hand grip strength was measured using hand dynamometer. DII scores were calculated from a 79-item food frequency questionnaire.
Results:
Fully adjusted linear regression models showed a statistically significant negative relationship between DII and ASM, ASM/Height², ASM/Weight, ALMI, TSM, TSM/Height², and TSM/Weight (p: 0.019‒0.014). The analysis of covariance indicated that the percentage differences in the extreme quartiles (Q4 vs Q1) of DII for the above-mentioned measures ranged from -1.04% to -4.36% (p-trend: <0.001‒0.013). When boys and girls were analyzed separately, similar findings were observed for boys but not for girls. No significant associations were detected between DII and hand grip strength.
Conclusions:
DII score was inversely associated with skeletal muscle mass in boys but not in girls aged 6-9 years old. No significant associations were observed between DII and hand grip strength.
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