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Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
Published on: September 26, 2019
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Competence in bronchoscopic treatments in emphysema
Michela Bezzi1, Valentina Luzzi2, Mauro Novali1
1Spedali Civili di Brescia, Brescia, Italy.
Panminerva Medica
|November 30, 2018
Summary
Bronchoscopic lung volume reduction (BLVR) effectively treats severe emphysema. Patient selection is crucial, as specific emphysema phenotypes benefit most from either blocking or non-blocking BLVR devices.
Area of Science:
- Pulmonology
- Interventional Pulmonology
- Medical Devices
Background:
- Severe emphysema impacts quality of life and lung function.
- Bronchoscopic lung volume reduction (BLVR) offers a less invasive treatment option.
- Patient selection is critical for successful BLVR outcomes.
Purpose of the Study:
- To review the effectiveness of BLVR in severe emphysema.
- To differentiate between blocking and non-blocking BLVR devices.
- To emphasize the importance of patient selection and fissure integrity assessment.
Main Methods:
- Review of current evidence on BLVR techniques.
- Discussion of blocking vs. non-blocking device mechanisms.
- Evaluation of fissure integrity assessment methods: Chartis system (direct) and CT scans (indirect).
Main Results:
- BLVR effectiveness varies by emphysema phenotype and device type.
- Blocking devices require collateral ventilation assessment; non-blocking devices do not.
- Accurate fissure integrity measurement is vital for treatment success.
Conclusions:
- Careful patient selection is imperative for optimal BLVR outcomes.
- Understanding emphysema phenotypes guides the choice of BLVR technique.
- Standardized training and certification are necessary for BLVR procedures.
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