Related Experiment Video
Updated: Feb 2, 2026

Determining the Egg Fertilization Rate of Bemisia tabaci Using a Cytogenetic Technique
Published on: April 1, 2019
Cumulative live birth rates in in-vitro fertilization
Panagiotis Drakopoulos1,2, Joaquín Errázuriz3,4,5, Samuel Santos-Ribeiro3,4,6
1Center for Reproductive Medicine, Brussels University Hospital, Brussels, Belgium - panagiotis.drakopoulos@uzbrussel.be.
Abstract:
Traditionally, in-vitro fertilization (IVF) success rates have been reported in terms of live birth per fresh cycle or embryo transfer. However, reporting IVF outcomes using cumulative live birth rates (LBR), defined as the first live birth following the use of all fresh and frozen embryos derived from a single ovarian stimulation cycle appears to be a better measure of IVF treatment success. Although there is an initial increase in fresh LBR with the number of oocytes retrieved, LBR either reach a plateau or may even decline when more than 15-20 oocytes are harvested. On the other hand, when all fresh and frozen embryos are taken into account, cumulative LBR have a significant positive association with ovarian response. Cumulative LBR are a more suitable are more comprehensive when reporting success in an IVF program. Cumulative LBR increase with the number of oocytes retrieved, suggesting that ovarian stimulation may have a minimal or no detrimental effect on oocyte/embryo quality.
Related Concept Videos
In Vitro Fertilization
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Birth Control Methods
Cumulative Frequency Distribution
Fertilization
Rate-Determining Steps
In a multistep reaction mechanism, one of the elementary steps progresses significantly slower than the others. This slowest step is called the rate-limiting step (or rate-determining step). A reaction cannot proceed faster than its slowest step, and hence, the rate-determining step limits the overall reaction rate.
The concept of rate-determining step can be understood from the analogy of a 4-lane freeway with a short-stretch of traffic-bottleneck caused due to...
Reaction Rate
The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...

