An update on the post-NICU discharge management of bronchopulmonary dysplasia

Anita Bhandari1, Howard Panitch1

  • 1Division of Pulmonary Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 11th floor Colket Building, 3501 Civic Center Boulevard, Philadelphia, PA 19446, United States.

Seminars in Perinatology
|November 30, 2018
PubMed

Insights

Bronchopulmonary dysplasia (BPD) is a common infant lung disease linked to prematurity. More research is needed on long-term outpatient treatments for established BPD after neonatal intensive care unit discharge.

Area of Science:

  • Neonatology
  • Pediatric Pulmonology
  • Chronic Lung Disease

Background:

  • Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in infancy, frequently linked to prematurity.
  • Rising BPD incidence correlates with increased survival rates of extremely premature infants.
  • Despite advances in neonatal care, data on established BPD outpatient management is limited.

Purpose of the Study:

  • To highlight the paucity of data on long-term outpatient management for established bronchopulmonary dysplasia.
  • To identify the need for high-quality research on commonly used therapies for BPD post-neonatal intensive care unit discharge.

Main Methods:

  • Review of existing literature on bronchopulmonary dysplasia management.
  • Analysis of the current evidence base for therapies including oxygen, bronchodilators, steroids, and diuretics.
  • Identification of research gaps in long-term outcome studies.

Main Results:

  • Limited high-quality studies and randomized controlled trials exist for outpatient BPD management.
  • Current research often focuses on short-term effects of therapies, not long-term outcomes.
  • Evidence is insufficient to guide optimal long-term treatment strategies for established BPD.

Conclusions:

  • Further research is crucial to understand the long-term impact of current treatments on patients with established BPD.
  • Improved understanding is needed for effective post-discharge care and management of BPD.
  • High-quality trials are necessary to inform evidence-based outpatient management of BPD.

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