Related Experiment Video

Updated: Feb 2, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
05:26

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

9.7K

Association of Prolonged QTc Dispersion with Diastolic Dysfunction of the Left Ventricle in Patients with Non ST

P Karmaker1, A K Choudhury, S Hashem

  • 1Dr Pranob Karmaker, Junior Consultant, Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ
|November 30, 2018
PubMed

Insights

Prolonged QTc dispersion is linked to left ventricular diastolic dysfunction in Non-ST Segment Elevation Myocardial Infarction patients with heart failure with preserved ejection fraction. This ECG finding aids in early detection and management.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Heart Failure Research

Background:

  • Diastolic dysfunction often precedes systolic decline and clinical symptoms in acute coronary syndrome.
  • Early diagnosis of diastolic dysfunction is crucial for managing heart failure with preserved ejection fraction (HFpEF).

Purpose of the Study:

  • To investigate the association between prolonged QTc dispersion and left ventricular diastolic dysfunction (LVDD) in Non-ST Segment Elevation Myocardial Infarction (NSTEMI) patients with HFpEF.

Main Methods:

  • A cross-sectional analytical study involving 60 NSTEMI patients, divided into two groups based on QTc dispersion (prolonged vs. normal).
  • Assessment of left ventricular diastolic dysfunction grades using echocardiography.
  • Statistical analysis to determine the association between QTc dispersion and LVDD severity.

Main Results:

  • A statistically significant association was found between prolonged QTc dispersion and Grade II (30.0% vs. 13.4%, p=0.001) and Grade III (40.0% vs. 10.0%, p=0.001) left ventricular diastolic dysfunction.
  • QTc dispersion significantly increased across the three grades of LVDD (p=0.007).
  • No significant association was observed for Grade I LVDD (p=0.16).

Conclusions:

  • Prolonged QTc dispersion is significantly associated with moderate to severe left ventricular diastolic dysfunction in NSTEMI patients with HFpEF.
  • Surface ECG-derived QTc dispersion is a valuable, non-invasive tool for predicting LVDD in this patient population.

More Related Videos

Myocardial Infarction and Functional Outcome Assessment in Pigs12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.7K
Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs08:19

Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs

Published on: July 12, 2022

3.5K

Related Concept Videos

Freezing Point Depression and Boiling Point Elevation03:12

Freezing Point Depression and Boiling Point Elevation

Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
40.1K
Distribution and Dispersion00:54

Distribution and Dispersion

To understand intra-specific interactions in populations, scientists measure the spatial arrangement of species individuals. This geographic arrangement is known as the species distribution or dispersion. Highly territorial species exhibit a uniform distribution pattern, in which individuals are spaced at relatively equal distances from one another. Species that are highly tied to particular resources, such as food or shelter, tend to concentrate around those resources, and thus exhibit a...
25.3K
Anatomy of the Brain: Ventricles01:18

Anatomy of the Brain: Ventricles

There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
9.0K
Elevation of Intermediate Points on Vertical Curves01:20

Elevation of Intermediate Points on Vertical Curves

Vertical curves are essential in roadway design because they provide smooth transitions between varying roadway grades. Designing vertical curves involves calculating intermediate elevations and identifying the curve's highest or lowest point, which is essential for optimal roadway performance.Intermediate elevations on a vertical curve are determined using the tangent offset method. This method considers the initial elevation at the start of the curve, the grades, and the curve's geometry. The...
295
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.4K
Associative Learning01:27

Associative Learning

Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
1.3K