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Updated: Feb 1, 2026

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
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How to Fluorescently Label the Potassium Channel: A Case in hERG

Xiaomeng Zhang1, Beilei Wang1, Zhenzhen Liu1

  • 1Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmacy, Shandong University, Jinan, Shandong 250012, China.

Current Medicinal Chemistry
|November 30, 2018
PubMed

Keywords:
Cryo- EM structurefluorophorehERG channelrecognition motifsmall molecule fluorescent probeturn-on switch.

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