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Related Concept Videos

Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

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Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
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Extraction: Advanced Methods00:56

Extraction: Advanced Methods

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Sample Preparation for Analysis: Advanced Techniques01:08

Sample Preparation for Analysis: Advanced Techniques

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Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
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Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

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Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
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Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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What is Cancer?02:12

What is Cancer?

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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
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Related Experiment Video

Updated: Feb 1, 2026

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
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Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

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Advanced prostate cancer update 2018.

Oliver Sartor1

  • 1Tulane Cancer Center, New Orleans, LA, USA.

Asia-Pacific Journal of Clinical Oncology
|November 30, 2018
PubMed
Summary
This summary is machine-generated.

Advanced prostate cancer management now integrates molecular pathology and genetics, shifting towards targeted therapies and novel radiopharmaceuticals. Future strategies emphasize precise patient selection and combination treatments for improved outcomes.

Keywords:
androgen receptorimagingprostate cancerradiopharmaceuticalstumor genetics

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Area of Science:

  • Oncology
  • Genetics
  • Molecular Medicine

Background:

  • Current advanced prostate cancer management employs a multidisciplinary strategy with multiple treatment targets.
  • Treatment paradigms have evolved from traditional hormonal therapy, surgery, and radiation to include chemotherapy, immunotherapy, and radiopharmaceuticals.

Purpose of the Study:

  • To review the latest perspectives in advanced prostate cancer treatment.
  • To discuss the integration of molecular pathology and genetics in treatment strategies.
  • To highlight emerging therapies including germline genetics, targeted therapies, and novel radiopharmaceuticals.

Main Methods:

  • Review of current literature on advanced prostate cancer management.
  • Discussion of recent advances in molecular pathology and genetics.
  • Analysis of new imaging techniques and staging for patient stratification.

Main Results:

  • Germline genetics, castrate-sensitive metastatic disease, androgen receptor alterations, targeted therapy, and novel radiopharmaceuticals represent new treatment perspectives.
  • Improved staging and imaging allow identification of patients suitable for localized treatments or intensive regimens.
  • Future management will likely involve careful patient selection and novel combination therapies.

Conclusions:

  • The management of advanced prostate cancer is increasingly personalized through molecular insights.
  • Novel targeted therapies and radiopharmaceuticals offer promising avenues for treatment.
  • Optimized patient selection and innovative combination regimens are crucial for future therapeutic success.