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Ibuprofen-induced meningitis in systemic lupus erythematosus
JAMA
|March 13, 1978
Summary
Ibuprofen ingestion can trigger meningitis in patients with systemic lupus erythematosus. Controlled drug rechallenge confirmed ibuprofen as the cause of meningitis in this case.
Area of Science:
- Neurology
- Rheumatology
- Pharmacology
Background:
- Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical manifestations.
- Drug-induced meningitis is a rare but serious adverse reaction to certain medications.
- The association between ibuprofen and meningitis in SLE patients has not been well-established.