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Related Concept Videos

Thermal Strain01:19

Thermal Strain

2.9K
Thermal strain is a concept that arises when we consider how temperature changes affect structures. Unlike the conventional assumption that structures remain constant under load, real-world scenarios often involve temperature fluctuations that can significantly impact these structures. Consider a homogeneous rod with a uniform cross-section resting freely on a flat horizontal surface. If the rod's temperature increases, the rod elongates. This elongation is proportional to the temperature...
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Shearing Strain01:20

Shearing Strain

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The shearing strain represents a cubic element's angular change when subjected to shearing stress. This type of stress can transform a cube into an oblique parallelepiped without influencing normal strains. The cubic element experiences a significant transformation when exposed solely to shearing stress. Its shape alters from a perfect cube into a rhomboid, clearly demonstrating the effect of shearing strain. The degree of this strain is considered positive if it reduces the angle between the...
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Measurements of Strain01:27

Measurements of Strain

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Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
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Strain Energy01:13

Strain Energy

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Strain energy is a fundamental concept in the field of materials science and structural engineering, describing the energy absorbed by a material or structure when it is deformed under load.
Consider a rod that is fixed at one end and subjected to an axial force at the free end. This axial force induces stress within the rod, leading to its elongation. As the axial force increases, so does the elongation of the rod, illustrating a direct relationship between the force applied and the resulting...
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Problem Solving on Stress and Strain01:22

Problem Solving on Stress and Strain

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Stress is a quantity that describes the magnitude of a force that causes deformation, generally defined as internal force per unit area. When forces pull on an object and cause its elongation, like the stretching of an elastic band, it is called tensile stress. When forces cause the compression of an object, it is known as compressive stress. When an object is being squeezed uniformly from all sides, like a submarine in the depths of the ocean, we call this kind of stress bulk stress (or volume...
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Stress-Strain Diagram01:10

Stress-Strain Diagram

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A stress-strain diagram is a crucial tool that graphically displays a material's mechanical characteristics. This diagram is derived from a tensile test performed on a carefully prepared cylindrical specimen. The specimen has two gauge marks inscribed on its central part, and the distance between these marks is known as the gauge length. The cylindrical specimen is placed in a testing machine, which applies an increasing centric load. As this load grows, so does the gauge length. This...
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Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
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Intraoperative Strain Elastosonography in Brain Tumor Surgery.

Francesco Prada1,2, Massimiliano Del Bene1,3, Angela Rampini1

  • 1Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Operative Neurosurgery (Hagerstown, Md.)
|November 30, 2018
PubMed
Summary

Strain elastography (SE) enhances brain tumor visualization and characterization in oncological neurosurgery. This ultrasound technique differentiates low-grade from high-grade gliomas, improving surgical precision.

Keywords:
Brain tumorGliomaIntraoperative imagingIntraoperative ultrasoundSonoelastographyStrain elastographyTumor stiffness

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Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Oncology

Background:

  • Sonoelastography (SE) is an ultrasound technique assessing tissue mechanical properties.
  • SE has broad clinical applications but limited use in brain tumor surgery.
  • This study explores SE's role in oncological neurosurgery.

Purpose of the Study:

  • To evaluate the large-scale implementation of SE in oncological neurosurgery.
  • To assess SE's utility in discriminating and characterizing brain lesions.
  • To compare SE with B-mode imaging for lesion assessment.

Main Methods:

  • Retrospective analysis of 64 patients undergoing oncological neurosurgery.
  • Evaluation of lesion and surrounding brain stiffness using SE.
  • Comparison of B-mode and SE for lesion morphology, margins, and dimensions.
  • Subgroup analysis for glioma characterization based on stiffness.

Main Results:

  • SE provided qualitative stiffness assessment for all lesions and surrounding brain.
  • Lesion morphology and margins were comparable or sharper in SE versus B-mode.
  • SE significantly differentiated low-grade gliomas (LGG) from high-grade gliomas (HGG) based on stiffness.
  • An SE score threshold of 2.5 demonstrated high sensitivity and specificity in differentiating LGG from HGG.

Conclusions:

  • SE enhances understanding of mechanical properties in brain lesions.
  • SE offers superior tissue discrimination compared to B-mode imaging.
  • SE effectively differentiates between low-grade and high-grade gliomas.