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Updated: Feb 1, 2026

Synthesis and Characterization of Amphiphilic Gold Nanoparticles
Published on: July 2, 2019
One-pot synthesis of gold nanoparticles embedded in polysaccharide-based hydrogel: Physical-chemical characterization
Morgana Souza Marques1, Κarine Modolon Zepon2, Julia Maia Heckler2
1Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina, 88701-000 Tubarão, SC, Brazil; Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, 90610-000 Porto Alegre, RS, Brazil(1).
Abstract:
In this study, polysaccharide-based hydrogel wound dressings containing in situ synthesized gold nanoparticles (AuNPs) were prepared by using a simple, fast and green protocol. The prepared hydrogels were characterized with UV-vis and infrared spectroscopy (FT-IR), and dynamic light scattering (DLS). The rheological and swelling properties and the feasibility to scale-up the wound dressing production from the lamination of the prepared hydrogel on non-woven fabric were also investigated. UV-vis spectra confirmed the AuNPs synthesis and the DLS results exhibited an increase in the size of AuNPs with increasing the initial Au3+ concentration. The rheological analysis showed that the augmentation of the initial Au3+ concentration reduces the gel viscosity and gelling temperature. Besides, the FT-IR spectra revealed that the AuNPs hinder the intermolecular interactions between kappa-carrageenan (κCG) and locust bean gum (LBG). The feasibility of scale-up the wound dressing production from the prepared hydrogel was confirmed through the lamination tests.
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