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[Current diagnosis and treatment progress of small pancreatic neuroendocrine neoplasm]

J L Jiang¹, W M Wu, Y P Zhao

¹Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]

|November 30, 2018

Abstract:

Small(≤2 cm)pancreatic neuroendocrine neoplasm(pNEN) is a very special subgroup of pNEN featuring a small size, concealed pathogenesis, indolent course and remarkable heterogeneity.Differences in its diagnosis and interventional criteria have evolved from routine pNEN.During recent years, the incidence of small pNEN has increased sharply, while optimal management strategy of this subgroup still remains controversial.In this paper, the biological characteristics, pathological classification, diagnosis, intervention indication and therapeutic principles of small pNEN are reviewed based on recent researches, and current situations of diagnosis and treatment of small pNEN are summarized.

Keywords:

Biological characteristics Diagnosis Neuroendocrine tumors Pathological classification Treatment

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