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Cutaneous Involvement of Hematologic Malignancies
Nancy Kaddis1, David Fisher2, Eric D Jacobsen2
1Department of Hematology and Oncology, Dana-Farber Cancer Institute at St Elizabeth's Medical Center, 736 Cambridge Street, Brighton, MA 02135, USA.
Abstract:
In reviewing cutaneous manifestations of various hematologic malignancies, the authors focus on secondary cutaneous lymphomas and cutaneous manifestations of histiocyte disorders. Secondary cutaneous lymphomas are defined as skin lesions that develop secondary to infiltration by systemic lymphomas with predominantly extracutaneous involvement. In their review of histiocytic disorders with skin involvement, the authors focus on Langerhans cell histiocytosis and Rosai-Dorfman disease. Their review emphasizes the histology, pathophysiology, clinical presentation, prognosis, and treatments available for these diseases.
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