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Updated: Feb 1, 2026

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
Published on: December 8, 2010
Cutaneous Metastasis
John D Strickley1, Alfred Bennett Jenson2, Jae Yeon Jung3
1James Graham Brown Cancer Center, University of Louisville School of Medicine, 529 S. Jackson Street, Louisville, KY 40202, USA; Department of Dermatology, Center for Cancer Immunology and Cutaneous Biology Research Center, MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
Abstract:
Although rare, cutaneous metastases portend a poor prognosis and are often an indicator of widespread disease. Breast cancer and melanoma are the most common types of cancer that are associated with spread to and within the skin; however, other malignancies, such as lung, colon, head and neck, and hematologic, have been described with a degree of relative frequency. A variety of clinical appearances and syndromes of cutaneous metastases are presented and described in this article. Possible treatment options, including skin-directed therapies and immunotherapies, are also discussed.

