Related Experiment Video
Updated: Feb 1, 2026

Author Spotlight: Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System
Published on: May 12, 2023
Evaluation of bioactivity and control efficacy of tetramycin against Corynespora cassiicola
Dicheng Ma1, Jiamei Zhu1, Jiangong Jiang1
1Shandong Provincial Key Laboratory for the Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural University, 61 Daizong Street, Tai'an, Shandong 271018, People's Republic of China.
Abstract:
Tetramycin is a novel polyene antibiotic that has exhibited excellent inhibitory activity against many plant pathogens. In this study, the sensitivity of Corynespora cassiicola to tetramycin was assessed in vitro using a series of 91 isolates, and its effects on hyphae and conidia were evaluated. Preventive and curative efficacies of tetramycin against Corynespora leaf spot were evaluated using detached cucumber leaves and potted cucumber plants. The control efficacy of tetramycin against the pathogen was also determined under field conditions. Measurement of baseline sensitivity suggested that the frequency distribution of tetramycin fits a unimodal curve. Among several life stages, spore germination was most severely inhibited by tetramycin, whereas mycelial growth was found to be the least sensitive. Microscopy observation revealed that tetramycin treatment leads to abnormal morphological development of C. cassiicola. Overall, tetramycin exhibited excellent curative and preventive activities against C. cassiicola on both cucumber leaves and potted cucumber plants. Furthermore, tetramycin significantly reduced the disease severity of Corynespora leaf spot in the field. The results from this study showed that tetramycin may play an important role in Corynespora leaf spot disease management and promote its introduction into fungicide-application programs.
Related Concept Videos
Self-Efficacy
Control System Problem
When forming a closed-loop system, issues can arise if the poles cross into the unstable region, leading to potential...
Dose-Response Relationship: Potency and Efficacy
Combinatorial Gene Control
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Control Systems
At the heart...

