Mini-electrodes help identifying hidden slow conduction during ventricular tachycardia substrate ablation.
David Soto-Iglesias1, David Andreu2, Beatriz Jáuregui1
1Hospital Clínic, Arrhythmia Section, Cardiology Department, Barcelona, Spain; Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Journal of Electrocardiology
|December 1, 2018
Summary
Mini-electrodes and extrastimuli successfully identified hidden slow conduction sites in a patient with dilated cardiomyopathy, enabling safe ablation of sustained monomorphic ventricular tachycardia (SMVT) during sinus rhythm.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Dilated non-ischemic cardiomyopathy can lead to sustained monomorphic ventricular tachycardia (SMVT).
- VT substrate ablation is challenging when the earliest activation site is near the conduction system.
- Previous ablation attempts may fail due to limitations in identifying critical slow conduction areas.
Observation:
- A 69-year-old male with a history of SMVT underwent an initial unsuccessful VT ablation.
- A second ablation attempt utilized a novel catheter with mini-electrodes (ME) and extrastimuli.
- This approach aimed to uncover hidden slow conduction (HSC) sites crucial for VT substrate.
Findings:
- ME-obtained electrograms accurately localized HSC sites within the VT substrate.
- The successful identification of HSC sites enabled precise ablation during sinus rhythm.
- Post-ablation, no further episodes of SMVT were induced, indicating a successful outcome.
Implications:
- Mini-electrode technology offers a promising method for precise VT substrate mapping.
- This technique facilitates safe and effective ablation of VT in complex cases.
- Improved identification of slow conduction can enhance outcomes for patients with cardiomyopathy and VT.
Related Concept Videos
Gene Evolution - Fast or Slow?
8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
8.2K
Gene Evolution - Fast or Slow?
3.7K
3.7K
Standard Electrode Potentials
50.3K
On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
50.3K
Conduction System of the Heart
13.4K
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
13.4K
Conduction System of the Heart
3.8K
The cardiac conduction system produces and transmits electrical impulses that prompt myocardial contraction, ensuring efficient heart function. This intricate system ensures that the heart beats in a coordinated and efficient manner, beginning with the atria and then the ventricles. The conduction system optimizes cardiac output by maintaining this precise sequence, which is crucial for adequate blood circulation.
This system relies on the unique properties of nodal and Purkinje cells:...
This system relies on the unique properties of nodal and Purkinje cells:...
3.8K
Conduct Disorder
567
Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
567


