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Related Experiment Videos

Sickle-cell anemia--a review.

S J Galloway1, A L Harwood-Nuss

  • 1Department of Surgery, University Hospital, Jacksonville, Florida 32209.

The Journal of Emergency Medicine
|May 1, 1988
PubMed
Summary
This summary is machine-generated.

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Sickle-cell anemia, a common blood disorder, presents serious complications. This review covers crises, management in emergency departments, and pain control for sickle-cell disease patients.

Area of Science:

  • Hematology
  • Genetics
  • Internal Medicine

Background:

  • Sickle-cell anemia affects over 50,000 Black individuals in the U.S.
  • Significant improvements in morbidity and mortality since 1970 allow patients to reach their fourth decade.
  • This article addresses the wide range of severe complications associated with sickle-cell anemia.

Purpose of the Study:

  • To discuss the spectrum of serious complications in sickle-cell anemia.
  • To present crises and complications arising from the sickling process.
  • To provide recommendations for emergency department evaluation and management of sickle-cell anemia.

Main Methods:

  • Review of the literature on sickle-cell anemia complications.
  • Discussion of clinical presentations of sickle-cell crises.

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  • Outline of emergency department protocols for sickle-cell disease management.

    • Main Results:

    • Sickle-cell anemia leads to diverse and serious complications.
    • Painful bone crises are a significant aspect of the disease.
    • Effective management strategies are crucial for improving patient outcomes.

    Conclusions:

    • Prompt evaluation and management are essential for sickle-cell crises.
    • Pain control is a critical component in managing sickle-cell anemia.
    • Understanding the spectrum of complications improves patient care and survival.