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Lanthanide chelates as new fluorochrome labels for cytochemistry

E J Soini1, L J Pelliniemi, I A Hemmilä

  • 1Wallac Oy, Turku, Finland.

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
|November 1, 1988
PubMed

Anti-rabbit IgG labeled with a new fluorescent europium chelate was used to localize rabbit IgG to human smooth muscle myosin in a histological section. The antibody labeled with the europium chelate could be viewed with a conventional fluorescence microscope with a steady-state light source. This result encourages the development of a time-resolved fluorescence microscope, because a significant improvement in the signal-to-noise ratio can be anticipated.

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