[Cytoflavin in the complex therapy of multiple sclerosis]

Area of Science:

• Neuroscience
• Pharmacology

Background:

• Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
• Exacerbations in relapsing-remitting MS require effective therapeutic strategies to manage neurological deficits.

Purpose of the Study:

• To assess the efficacy of cytoflavin as an add-on therapy for patients with relapsing-remitting multiple sclerosis during acute exacerbations.
• To determine if cytoflavin improves outcomes when combined with standard hormonal therapy.

Main Methods:

• A study involving 41 patients with multiple sclerosis undergoing treatment for exacerbations.
• Patients were divided into two groups: one receiving hormonal therapy (methylprednisolone) and the other receiving hormonal therapy plus cytoflavin.
• Treatment efficacy was evaluated using clinical assessments (FS, EDSS scales), laboratory markers, and neuroimaging, with assessments conducted before, during, and after treatment.

Main Results:

• Patients receiving cytoflavin showed a significant reduction in the severity of neurological symptoms compared to the control group.
• Improvements were observed in visual system disorders in the cytoflavin group.
• A lower incidence of non-response to treatment was noted in patients who received cytoflavin.

Conclusions:

• Cytoflavin acts as an effective antioxidant and neuroprotective agent in the acute phase of multiple sclerosis.
• Its inclusion in complex therapy enhances the efficacy of basic hormonal treatment.
• Cytoflavin offers a promising therapeutic option for managing MS exacerbations, improving patient outcomes.