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[The feasibility of using Quick Dementia Rating System in clinical practice: results of a multi-center prospective
O S Levin1, E E Vasenina1, A G Sonin2
1Russian Medical Academy of Continuous Professional Education, Moscow, Russia.
Aim:
To determine the sensitivity and specificity of the Quick Dementia Rating System (QDRS), a 10-item questionnaire for the assessment of cognitive, behavioral, and functional impairments, in the Russian population.
Material And Methods:
The authors examined 2357 patients,1479 female (63%) and 878 male (37%), with subjective cognitive impairment (SCI), mild cognitive impairment (MCI) or dementia. Their average age was 73,1±9,7. All patients were assessed using QDRS and MMSE on baseline visits and reassessed after 1, 3, and 6 months.
Results:
The sensitivity and specificity of QDRS were 79,2% and 81,2%, respectively, at cut-interval of more than 7 points. There was a strong inverse correlation between QDRS and MMSE indicators (r=-0,740). QDRS was the most sensitive for the detection of severe dementia (sensitivity of 78,2% and specificity of 85,2%), while for mild and moderate dementia the sensitivity was high (79,4% and 81,6%) and specificity was low (56,6% and 61,9%, respectively). The sensitivity and specificity of separate subtests were variable.
Conclusion:
The QDRS sensitivity and specificity allow recommending it for clinical practice. The questionnaire is the most sensitive to detect more severe cognitive impairment.
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