Enhancing the dynamic range of phase-sensitive optical coherence elastography by overcoming speckle decorrelation
Optics Letters
|December 1, 2018
Summary
Phase-sensitive optical coherence elastography (PhS-OCE) now tracks larger displacements. A new method enhances PhS-OCE
Area of Science:
- Biomedical Optics
- Materials Science
- Mechanical Engineering
Background:
- Phase-sensitive optical coherence elastography (PhS-OCE) offers sub-nanometer displacement sensitivity for semi-transparent materials.
- Existing PhS-OCE methods face a limited dynamic range (micrometers) due to speckle decorrelation.
Purpose of the Study:
- To develop a novel displacement tracking method to overcome the dynamic range limitation of PhS-OCE.
- To enable quantitative detection of previously unmeasurable mechanical behaviors in materials.
Main Methods:
- A new displacement tracking approach utilizing a subset-based match algorithm.
- Employing the noise number of the phase difference map as a quality indicator for tracking accuracy.
- Validation using polymer samples subjected to temperature and mechanical loading.
Main Results:
- The developed method successfully tracks both axial and lateral displacements beyond the conventional PhS-OCE limits.
- Quantitative measurements of displacements induced by thermal and mechanical stimuli were achieved.
- Previously undetectable mechanical behaviors within polymer samples were identified.
Conclusions:
- The enhanced PhS-OCE method significantly expands the dynamic range of displacement measurements.
- This advancement allows for more comprehensive characterization of material mechanical properties.
- The technique holds potential for broader applications in materials science and biomedical imaging.
More Related Videos
Related Concept Videos
01:22Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems
212
Body:Bioavailability is a critical pharmacological concept that measures the extent and rate at which an active drug ingredient or therapeutic moiety enters the systemic circulation, remaining unchanged. It's a pivotal factor in determining a drug's efficacy and safety.The Biopharmaceutics Classification System (BCS) plays an essential role in drug development by categorizing drugs into four classes based on their solubility and permeability. This classification aids in understanding drug...
212
02:33Phase Transitions: Sublimation and Deposition
20.2K
Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
20.2K
00:59Range
14.2K
The range is one of the measures of variation. It can be defined as the difference between a dataset's highest and lowest values. For example, in the study of seven 16-ounce soda cans, the filled volume of soda was measured, thus producing the following amount (in ounces) of soda:
15.9; 16.1; 15.2; 14.8; 15.8; 15.9; 16.0; 15.5
Measurements of the amount of soda in a 16-ounce can vary since different subjects record these measurements or since the exact amount - 16 ounces of liquid, was not...
15.9; 16.1; 15.2; 14.8; 15.8; 15.9; 16.0; 15.5
Measurements of the amount of soda in a 16-ounce can vary since different subjects record these measurements or since the exact amount - 16 ounces of liquid, was not...
14.2K
03:00Self-Evaluation: Self-Enhancement and Self-Verification
5.8K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
5.8K
02:31Phase Transitions
23.2K
Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
23.2K
02:39Phase Transitions: Vaporization and Condensation
21.3K
The physical form of a substance changes on changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. Vaporization occurs when the thermal motion of the molecules overcome the intermolecular forces, and the molecules (at the surface) escape into the gaseous state. When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules...
21.3K