Related Experiment Video
Updated: Feb 1, 2026

Rod-based Fabrication of Customizable Soft Robotic Pneumatic Gripper Devices for Delicate Tissue Manipulation
Published on: August 2, 2016
Experience with 102 Frameless Stereotactic Biopsies Using the neuromate Robotic Device
Hamzah Yasin1, Hans-Joachim Hoff1, Ingmar Blümcke2
1Department of Neurosurgery, Bethel Clinic, Bielefeld, Germany.
Robot-assisted frameless stereotactic biopsy using the neuromate robot is a safe and effective alternative to traditional frame-based methods. This technique achieved a high diagnostic yield with comparable complication rates for neurosurgery patients.
Area of Science:
- Neurosurgery
- Robotic Surgery
- Neuropathology
Background:
- Stereotactic biopsy is a cornerstone of neurosurgical diagnosis.
- Frameless and robotic systems are emerging alternatives to frame-based stereotaxy.
- The neuromate robotic device offers a novel approach to frameless stereotactic biopsy.
Purpose of the Study:
- To evaluate the efficacy and safety of the neuromate robotic system for frameless stereotactic biopsies.
- To analyze histopathologic results, complication rates, and procedure duration.
- To compare robot-assisted biopsies with traditional frame-based stereotaxy.
Main Methods:
- Retrospective analysis of 102 consecutive robot-assisted frameless biopsies using the neuromate device.
- Patients underwent biopsy for deep-seated or small lesions.
- Histopathologic outcomes, complications, and procedure times were recorded.
Main Results:
- A definitive histologic diagnosis was achieved in 92.2% of procedures.
- No infectious complications occurred.
- Biopsy-related hemorrhages (>10 mm) occurred in 12.7% of cases, with persistent neurologic worsening in only 2.9%.
Conclusions:
- Robot-assisted frameless stereotactic biopsies with the neuromate robot are a viable alternative to frame-based stereotaxy.
- The diagnostic yield is similar to traditional methods.
- Complication rates are comparable, demonstrating the safety and efficacy of the robotic approach.
Related Concept Videos
What is an Experiment?
Thomson's e/m Experiment
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...
Controls in Experiments
Randomized Experiments
Simple randomization
Simple...
Crossover Experiments
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
The Stanford Prison Experiment

