Related Experiment Video
Updated: Feb 1, 2026

Permeabilization of Adhered Cells Using an Inert Gas Jet
Published on: September 4, 2013
A nozzle for high-density supersonic gas jets at elevated temperatures.
C M Heyl1, S B Schoun1, G Porat1
1JILA, NIST and the University of Colorado, 440 UCB, Boulder, Colorado 80309-0440, USA.
We developed a fused silica gas nozzle that delivers high-density, hot gas jets for high-order harmonic generation experiments. This design enhances laser-gas interactions in vacuum environments.
Area of Science:
- Plasma Physics
- Laser-Matter Interaction
- Materials Science
Background:
- High-power laser systems require precise gas delivery for experiments.
- Traditional gas nozzles can be damaged by proximity to intense laser beams.
- Efficient gas replenishment is crucial for repetitive laser-gas interaction studies.
Purpose of the Study:
- To develop a novel gas nozzle for high-density, high-temperature gas jets in vacuum.
- To enable close proximity of the nozzle tip to high-power laser beams.
- To improve gas replenishment for laser-gas interaction experiments.
Main Methods:
- Utilized fused silica as the nozzle material for laser compatibility.
- Integrated heater wires to achieve nozzle temperatures up to 730 °C.
- Employed a cooling unit to maintain nozzle mount below 50 °C.
- Designed a 50 μm opening for supersonic gas jet generation.
Main Results:
- Successfully generated high-density supersonic gas jets at elevated temperatures.
- Fused silica nozzle minimized material sputtering into the vacuum chamber.
- Achieved increased gas-jet velocity for efficient interaction region replenishment.
- Demonstrated nozzle operation with gas backing pressures up to 124 bars.
Conclusions:
- The developed fused silica gas nozzle effectively provides hot, high-density gas jets for laser-gas interactions.
- This design is suitable for high-order harmonic generation experiments in vacuum.
- The nozzle's material and temperature control enhance durability and experimental efficiency.
Related Concept Videos
Applications of the Ideal Gas Law: Molar Mass, Density, and Volume
Freezing Point Depression and Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
Free Jet
Kinetic Molecular Theory and Gas Laws Explain Properties of Gas Molecules
Temperature Dependence on Reaction Rate
Atoms, molecules, or ions must collide before they can react with each other. Atoms must be close together to form chemical bonds. This premise is the basis for a theory that explains many observations regarding chemical kinetics, including factors affecting reaction rates.
The collision theory is based on the postulates that (i) the reaction rate is proportional to the rate of reactant collisions, (ii) the reacting species collide in an orientation allowing contact between...
Gas Laws: Boyle's, Gay-Lussac, Charles', Avogadro's, and Ideal Gas Law

