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Updated: Feb 1, 2026

Live-cell Imaging of Fungal Cells to Investigate Modes of Entry and Subcellular Localization of Antifungal Plant Defensins
Published on: December 24, 2017
Antibacterial Activity of Plant Defensins
Andrew E Sathoff1, Deborah A Samac1,2
11 Department of Plant Pathology, 1991 Upper Buford Circle, University of Minnesota, St. Paul, MN, 55108, U.S.A.; and.
Abstract:
Plant defensins are antimicrobial host defense peptides expressed in all higher plants. Performing a significant role in plant innate immunity, plant defensins display potent activity against a wide range of pathogens. Vertebrate and invertebrate defensins have well-characterized antibacterial activity, but plant defensins are commonly considered to display antimicrobial activity against only fungi. In this review, we highlight the often-overlooked antibacterial activity of plant defensins. Also, we illustrate methods to evaluate defensins for antibacterial activity and describe the current advances in uncovering their antibacterial modes of action.
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