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Updated: Feb 1, 2026

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
Published on: February 24, 2016
Evaluation of Plastic-Compressed Collagen for Conjunctival Repair in a Rabbit Model
Joana Witt1, Maria Borrelli1, Sonja Mertsch1
1Department of Ophthalmology, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Impact Statement:
Conjunctival integrity is crucial for a healthy ocular surface and visual acuity. In severe cases of inflammatory surface disorders or after trauma, thermal or chemical burns as well as after ocular surgery, a surgical reconstruction using conjunctival substitutes is required. Due to limitations of currently used substitutes, such as the amniotic membrane, there is a need for the development of new scaffolds of consistent quality for conjunctival reconstruction. This study explored the biocompatibility and surgical usability of plastic-compressed collagen as an alternative conjunctival substitute in a rabbit model.
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