Related Experiment Video
Updated: Feb 1, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Oxazole-Based Compounds As Anticancer Agents
Maria A Chiacchio1, Giuseppe Lanza1, Ugo Chiacchio1
1Dipartimento di Scienze del Farmaco, University of Catania, V.le Doria 6, 95125 Catania, Italy.
Abstract:
Heterocyclic compounds represent a significant target for anti-cancer research and drug discovery, due to their structural and chemical diversity. Oxazoles, with oxygen and nitrogen atoms present in the core structure, enable various types of interactions with different enzymes and receptors, favoring the discovery of new drugs. Aim of this review is to describe the most recent reports on the use of oxazole-based compounds in anticancer research, with reference to the newly discovered iso/oxazole-based drugs, to their synthesis and to the evaluation of the most biologically active derivatives. The corresponding dehydrogenated derivatives, i.e. iso/oxazolines and iso/oxazolidines, are also reported.
Related Concept Videos
Organic Compounds
Molecules and Compounds
Coordination Compounds and Nomenclature
Elements and Compounds
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
Molecular Compounds: Formulas and Nomenclature
Ionic Compounds: Formulas and Nomenclature

