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[Eosinopenia in 2018].

H Gil1, B Bouldoires1, B Bailly1

  • 1Service de médecine interne, CHU Jean-Minjoz, 25000 Besançon, France.

La Revue De Medecine Interne
|December 4, 2018
PubMed
Summary
This summary is machine-generated.

Eosinopenia, a long-standing biological test, aids in diagnosing bacterial infections and serves as a reliable mortality marker. Its diagnostic value is comparable to procalcitonin but at no extra cost.

Keywords:
Bacterial infectionEosinopeniaInfections bactériennesPolynuclear eosinophilPolynucléaires éosinophilesÉosinopénie

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Area of Science:

  • Clinical Pathology
  • Infectious Disease Diagnostics
  • Biomarker Research

Background:

  • Eosinopenia has been utilized since 1893 as a diagnostic indicator for bacterial infections.
  • Its utility is well-documented in critical care, pulmonology, and pediatric settings.
  • Previous studies highlight its significance in managing cerebrovascular diseases and post-coronary bypass patients.

Purpose of the Study:

  • To evaluate the diagnostic and prognostic value of eosinopenia in bacterial infections.
  • To assess the impact of the CIBLE score on enhancing eosinopenia's diagnostic performance.
  • To determine the reliability of eosinopenia monitoring as a mortality predictor.

Main Methods:

  • Review of existing literature and clinical data on eosinopenia.
  • Analysis of diagnostic performance metrics in various clinical units.
  • Evaluation of the CIBLE score's contribution to eosinopenia-based diagnosis.
  • Assessment of eosinopenia trends in relation to patient mortality.

Main Results:

  • Eosinopenia demonstrates significant diagnostic value for bacterial infections, comparable to procalcitonin.
  • The CIBLE score enhances the diagnostic accuracy of eosinopenia in routine clinical practice.
  • Monitoring eosinopenia levels provides a reliable indicator of patient mortality risk.

Conclusions:

  • Eosinopenia is a cost-effective and valuable biomarker for diagnosing bacterial infections.
  • The CIBLE score improves the clinical utility of eosinopenia.
  • Eosinopenia monitoring is a significant prognostic tool for patient outcomes.