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Acute Pancreatitis II: Clinical Manifestations and Management01:30

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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A decreasing function describes a relationship where the output consistently declines as the input increases. This means that for any two input values, if one is greater than the other, the corresponding output is smaller. Mathematically, a function f is decreasing on an interval I if for every x1 < x2​ in I, f (x1) > f (x2). This type of behavior is visually identified on a graph that slopes downward from left to right.The nature of a function can be analyzed by calculating...
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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
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Endoscopic intervention and cholecystectomy in pregnant women with acute biliary pancreatitis decrease early

Anjuli K Luthra1, Kishan P Patel2, Feng Li1

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Pregnant women with acute biliary pancreatitis face higher readmission risks. Less frequent ERCP and cholecystectomy during pregnancy contribute to this, suggesting these procedures could reduce readmissions.

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Area of Science:

  • Gastroenterology
  • Obstetrics & Gynecology
  • Public Health

Background:

  • Acute biliary pancreatitis (ABP) presents increased morbidity risks during pregnancy.
  • Population-based studies on ABP in pregnancy are scarce, necessitating national-level outcome analysis.

Purpose of the Study:

  • To investigate clinical outcomes of hospitalized pregnant women with ABP.
  • To evaluate the impact of pregnancy on early readmission and severe acute pancreatitis (SAP) in ABP patients.

Main Methods:

  • Utilized the Nationwide Readmission Database (2011-2014) for US hospitalizations of women aged ≥18 with ABP.
  • Employed multivariate and propensity-score matched analyses to compare outcomes between pregnant and non-pregnant women.

Main Results:

  • Pregnant women with ABP had a 16.26% 30-day readmission rate, with 57% due to ABP adverse events.
  • Pregnancy was associated with increased 30-day readmission risk (OR, 1.96) but not SAP risk (OR, 1.09).
  • ERCP and cholecystectomy were performed less frequently in pregnant women, and these procedures reduced readmission odds.

Conclusions:

  • Pregnant women with ABP undergo less frequent endoscopic biliary decompression and cholecystectomy.
  • Timely intervention with ERCP and cholecystectomy may reduce early readmissions in pregnant women with ABP.