Related Experiment Video
Updated: Feb 1, 2026
10:03
Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
Published on: June 27, 2025
785
[Pulmonary hypertension as presentation in multiple myeloma]
Fernando Di Tullio1, Glenda Ernst1, Félix Vigovich1
1Centro de Medicina Respiratoria, Hospital Británico de Buenos Aires, Argentina.
Medicina
|December 4, 2018
Summary
This case study highlights a rare instance of multiple myeloma in a young woman, presenting with unusual cardiac and pulmonary symptoms. Early diagnosis is crucial for managing this hematologic malignancy.
Area of Science:
- Hematology
- Cardiology
- Pulmonology
Background:
- Multiple myeloma is a plasma cell malignancy, typically affecting older adults.
- It rarely occurs in patients under 40, representing only 2% of cases.
Observation:
- A 36-year-old female with a significant smoking history presented with dyspnea and right heart overload.
- Clinical findings included anemia, proteinuria, elevated inflammatory markers, and restrictive spirometry with reduced diffusing capacity for carbon monoxide (DLCO).
Findings:
- Echocardiography revealed right heart dilation and pulmonary hypertension.
- Right heart catheterization confirmed pulmonary hypertension, leading to the diagnosis of multiple myeloma.
Implications:
- This case underscores the importance of considering multiple myeloma in young adults presenting with atypical cardiopulmonary symptoms.
- It highlights the need for comprehensive diagnostic workups to identify rare presentations of hematologic malignancies.
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