Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lung Capacity01:47

Lung Capacity

56.3K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.3K
Pleura of the Lungs01:13

Pleura of the Lungs

7.3K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
7.3K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.1K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.1K
Gross Anatomy of the Lungs01:17

Gross Anatomy of the Lungs

4.7K
The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
4.7K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

2.4K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
2.4K
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

1.2K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Food is the Best Medicine (FBM): design and baseline findings from a multi-arm randomized controlled trial among food-insecure postpartum mothers in Texas.

BMC nutrition·2026
Same author

Structure-function relationships governing the multimodal antioxidant protection of quinoa protein hydrolysates.

Food chemistry·2026
Same author

[Neuropsychiatric Effects of Creatine: What Does the Preclinical and Clinical Evidence Conclude?]

Revista medica de Chile·2026
Same author

Implementation of the first adolescence-to-adulthood transition programme for Multiple Sclerosis in Latin America.

Multiple sclerosis and related disorders·2026
Same author

Gait Disturbance Secondary to Scurvy in Patients with ASD and Avoidant/Restrictive Food Intake Disorder (ARFID): Presentation of a Case Series.

Journal of autism and developmental disorders·2026
Same author

Systematic Review and Network Meta-Analysis of Initial Treatments for Lupus Nephritis.

Kidney international reports·2025

Related Experiment Video

Updated: Feb 1, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.9K

[IgG4-related interstitial lung disease].

Pablo Idoyaga1, Mariano Fielli2, Alejandra González2

  • 11Servicio de Neumonología, Hospital Nacional Profesor Alejandro Posadas, El Palomar, Buenos Aires, Argentina.

Medicina
|December 4, 2018
PubMed
Summary

This case study highlights IgG4-related disease, a complex condition. Early diagnosis and immunosuppressive therapy are crucial for managing its diverse systemic manifestations.

Keywords:
IgG4IgG4 related lung diseaseinterstitial lung disease

More Related Videos

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

52.0K
Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling
05:47

Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling

Published on: February 12, 2019

22.1K

Related Experiment Videos

Last Updated: Feb 1, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.9K
Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

52.0K
Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling
05:47

Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling

Published on: February 12, 2019

22.1K

Area of Science:

  • Immunology
  • Rheumatology
  • Pulmonology

Background:

  • IgG4-related disease (IgG4-RD) is a chronic, fibroinflammatory condition.
  • It can affect multiple organs, presenting a diagnostic challenge.
  • Systemic involvement necessitates a comprehensive diagnostic approach.

Observation:

  • A 55-year-old female presented with respiratory failure, initially treated as pneumonia.
  • Recurrence of symptoms included subglottic stenosis and gland enlargement.
  • Imaging revealed diffuse ground glass opacities and reticular patterns.

Findings:

  • Transbronchial and salivary gland biopsies confirmed IgG4-positive plasma cell infiltration.
  • Elevated serum IgG4 levels supported the diagnosis.
  • Prompt response to corticosteroids and immunosuppressive therapy was observed.

Implications:

  • This case underscores the importance of considering IgG4-RD in patients with unexplained multi-organ inflammation.
  • Timely diagnosis and targeted immunosuppression can significantly improve patient outcomes.
  • Further research into IgG4-RD pathogenesis and treatment is warranted.