Related Experiment Video

Updated: Feb 1, 2026

Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers
11:34

Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers

Published on: December 5, 2017

13.1K

ZW25 Effective in HER2-Positive Cancers

    Cancer Discovery
    |December 4, 2018
    PubMed
    Summary

    A new therapy targeting HER2-positive cancers, ZW25, shows promise in early trials. This novel anti-HER2 drug demonstrated a 41% response rate with manageable side effects in patients with various HER2-positive tumors.

    More Related Videos

    A Syngeneic Pancreatic Cancer Mouse Model to Study the Effects of Irreversible Electroporation08:05

    A Syngeneic Pancreatic Cancer Mouse Model to Study the Effects of Irreversible Electroporation

    Published on: June 8, 2018

    12.0K
    Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation10:21

    Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation

    Published on: December 25, 2017

    14.2K

    Related Concept Videos

    Position-effect Variegation02:32

    Position-effect Variegation

    In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
    7.1K
    Chromatin Position Affects Gene Expression02:35

    Chromatin Position Affects Gene Expression

    Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
    Topologically Associated Domains (TADs)
    The 3-dimensional positioning of chromatin in the nucleus influences the...
    24.8K
    Position and Displacement01:31

    Position and Displacement

    The position of an object defines its location relative to a convenient frame of reference at any particular time. A frame of reference is an arbitrary set of axes from which the position and motion of an object are described. Earth is often used as a frame of reference, and we often describe the position of an object as it relates to stationary objects on Earth. For example, a rocket launch could be described in terms of the position of the rocket with respect to Earth as a whole. On the other...
    25.9K
    Serial Position Effect01:03

    Serial Position Effect

    The serial position effect is a cognitive phenomenon where individuals are more likely to recall the first and last items in a list compared to those in the middle. This effect is divided into the primacy effect and the recency effect. The primacy effect is observed when the initial items in a list are remembered better. This occurs because these items are rehearsed more frequently or receive more elaborative processing, allowing them to be encoded into long-term memory more effectively. For...
    543
    Framing Effects03:26

    Framing Effects

    Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in...
    7.9K
    Position Vectors01:29

    Position Vectors

    A position vector is a fundamental concept in mathematics that helps determine the position of one point with respect to another point in space. It is a vector that describes the direction and distance between two points. Position vectors are highly useful in the field of math and science, as they help represent spatial relationships and make calculations easier.
    For instance, we want to locate a point P(x, y, z) relative to the origin of coordinates O. In that case, we can define a position...
    1.9K