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Case-based roundtable on treatment approach for young, fit, newly diagnosed multiple myeloma patients

Sergio Giralt1, Eric Seifter2

  • 1Division of Hematologic Oncology, Memorial Sloan Kettering Cancer Center, New York, NY; and.

Hematology. American Society of Hematology. Education Program
|December 4, 2018
PubMed

Insights

The therapeutic landscape for multiple myeloma has evolved with new drug approvals. This guide details a 2018 approach to treating transplant-eligible patients with these novel therapies.

Area of Science:

  • Hematology
  • Oncology
  • Pharmacology

Background:

  • The treatment of multiple myeloma has been significantly impacted by recent advancements in therapeutic options.
  • New classes of drugs, including proteasome inhibitors, immune-modulatory drugs, and monoclonal antibodies, have been approved.

Purpose of the Study:

  • To provide a personal, case-based guide on managing multiple myeloma therapy.
  • To outline an approach for transplant-eligible patients in the context of 2018 treatment options.

Main Methods:

  • A case-based approach is utilized to illustrate therapeutic decision-making.
  • The guide incorporates newly approved agents such as carfilzomib, ixazomib, pomalidomide, elotuzimab, and daratumumab.

Main Results:

  • The evolving treatment landscape necessitates personalized therapeutic strategies.
  • Effective management involves integrating novel agents into treatment regimens.

Conclusions:

  • A structured, case-based approach is essential for optimizing multiple myeloma treatment.
  • The integration of novel therapies offers improved management options for transplant-eligible patients.

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